论文标题
修改生存模型以适应阈值行为
Modifying Survival Models To Accommodate Thresholding Behavior
论文作者
论文摘要
生存模型捕获了积累危险与该积累刺激的单数事件发生之间的关系。当危险模型足够灵活的生存模型时,可以容纳广泛的行为。如果危险模型的灵活性较小,例如,当它受到外部物理过程的限制时,则结果生存模型可能太僵硬了。在本文中,我介绍了一个修改的生存模型,该模型概括了积累危害与事件发生之间的关系,并特别强调捕获阈值行为。最后,我证明了这种方法在生理应用上的实用性。
Survival models capture the relationship between an accumulating hazard and the occurrence of a singular event stimulated by that accumulation. When the model for the hazard is sufficiently flexible survival models can accommodate a wide range of behaviors. If the hazard model is less flexible, for example when it is constrained by an external physical process, then the resulting survival model can be much too rigid. In this paper I introduce a modified survival model that generalizes the relationship between accumulating hazard and event occurrence with particular emphasis on capturing thresholding behavior. Finally I demonstrate the utility of this approach on a physiological application.