论文标题

通过几何深度学习标记自动冠状动脉

Automated Coronary Arteries Labeling Via Geometric Deep Learning

论文作者

Li, Yadan, Armin, Mohammad Ali, Denman, Simon, Ahmedt-Aristizabal, David

论文摘要

解剖结构(例如冠状动脉)的自动标记对于诊断至关重要,但是现有的(非深度学习)方法受到对预期树状结构的先前拓扑知识的依赖的限制。由于这种血管系统通常很难概念化,因此基于图的表示由于其能够以与方向无关和抽象的方式捕获形态的几何和拓扑特性的能力。然而,基于图的学​​习,用于树状解剖结构的自动标记,在文献中受到了有限的关注。大多数先前的研究在实体图构造中都有局限性,取决于拓扑结构,并且由于受试者之间的解剖学变异性而导致的准确性有限。在本文中,我们提出了一种直观的图表方法,非常适合与从血管造影扫描获得的3D坐标数据一起使用。随后,我们寻求使用几何深度学习来分析特定于主题的图。提出的模型利用了141名患者的专家注释标签来学习每个冠状动脉片段的表示,同时捕获训练数据中解剖学变异性的影响。我们研究了通过神经网络的所谓消息的不同变体。通过广泛的评估,我们的管道实现了标签冠状动脉(13类)的有希望的加权F1评分,用于五倍的交叉验证。考虑到图形模型处理不规则数据的能力及其对数据分割的可扩展性,这项工作突出了此类方法提供定量证据以支持医疗专家的决策的潜力。

Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As the structure such vascular systems is often difficult to conceptualize, graph-based representations have become popular due to their ability to capture the geometric and topological properties of the morphology in an orientation-independent and abstract manner. However, graph-based learning for automated labeling of tree-like anatomical structures has received limited attention in the literature. The majority of prior studies have limitations in the entity graph construction, are dependent on topological structures, and have limited accuracy due to the anatomical variability between subjects. In this paper, we propose an intuitive graph representation method, well suited to use with 3D coordinate data obtained from angiography scans. We subsequently seek to analyze subject-specific graphs using geometric deep learning. The proposed models leverage expert annotated labels from 141 patients to learn representations of each coronary segment, while capturing the effects of anatomical variability within the training data. We investigate different variants of so-called message passing neural networks. Through extensive evaluations, our pipeline achieves a promising weighted F1-score of 0.805 for labeling coronary artery (13 classes) for a five-fold cross-validation. Considering the ability of graph models in dealing with irregular data, and their scalability for data segmentation, this work highlights the potential of such methods to provide quantitative evidence to support the decisions of medical experts.

扫码加入交流群

加入微信交流群

微信交流群二维码

扫码加入学术交流群,获取更多资源