论文标题

使用生物力学的建模从图像中学习心脏运动的对应

Learning correspondences of cardiac motion from images using biomechanics-informed modeling

论文作者

Zhang, Xiaoran, You, Chenyu, Ahn, Shawn, Zhuang, Juntang, Staib, Lawrence, Duncan, James

论文摘要

从图像中学习心脏运动中的时空对应关系对于理解心脏解剖结构的潜在动力学很重要。许多方法明确施加了平滑度约束,例如位移矢量字段(DVF)上的$ \ Mathcal {l} _2 $ NORM,而通常忽略转换中的生物力学可行性。其他几何约束可以使特定感兴趣的特定区域(例如在心肌上施加不可压缩性)或引入其他步骤,例如在物理模拟的数据集中训练单独的基于网络的正规器。在这项工作中,我们提出了一个明确的生物力学知识,因为在所有心脏结构中,在没有引入额外的训练复杂性的情况下,在所有心脏结构内建模更通用的生物力学上可行的转换时,对预测的DVF进行了正则化。在2D MRI数据的背景下,我们验证了两个公开可用数据集的方法,并执行广泛的实验,以说明与其他竞争正规化方案相比,我们提出的方法的有效性和鲁棒性。我们提出的方法可以通过视觉评估更好地保留生物力学特性,并使用定量评估指标显示分割性能的优势。该代码可在\ url {https://github.com/voldemort108x/bioinformed_reg}上公开获得。

Learning spatial-temporal correspondences in cardiac motion from images is important for understanding the underlying dynamics of cardiac anatomical structures. Many methods explicitly impose smoothness constraints such as the $\mathcal{L}_2$ norm on the displacement vector field (DVF), while usually ignoring biomechanical feasibility in the transformation. Other geometric constraints either regularize specific regions of interest such as imposing incompressibility on the myocardium or introduce additional steps such as training a separate network-based regularizer on physically simulated datasets. In this work, we propose an explicit biomechanics-informed prior as regularization on the predicted DVF in modeling a more generic biomechanically plausible transformation within all cardiac structures without introducing additional training complexity. We validate our methods on two publicly available datasets in the context of 2D MRI data and perform extensive experiments to illustrate the effectiveness and robustness of our proposed methods compared to other competing regularization schemes. Our proposed methods better preserve biomechanical properties by visual assessment and show advantages in segmentation performance using quantitative evaluation metrics. The code is publicly available at \url{https://github.com/Voldemort108X/bioinformed_reg}.

扫码加入交流群

加入微信交流群

微信交流群二维码

扫码加入学术交流群,获取更多资源