论文标题

超声成像中的胎盘分割:解决不确定性来源和有限的视野

Placenta Segmentation in Ultrasound Imaging: Addressing Sources of Uncertainty and Limited Field-of-View

论文作者

Zimmer, Veronika A., Gomez, Alberto, Skelton, Emily, Wright, Robert, Wheeler, Gavin, Deng, Shujie, Ghavami, Nooshin, Lloyd, Karen, Matthew, Jacqueline, Kainz, Bernhard, Rueckert, Daniel, Hajnal, Joseph V., Schnabel, Julia A.

论文摘要

胎盘超声(US)中胎盘的自动分割由于(i)(i)胎盘外观的高度多样性,(ii)US导致高度可变的参考注释的限制质量,以及(iii)US访问量的有限视野,禁止延迟胎儿评估整个胎盘评估。在这项工作中,我们通过多任务学习方法解决了这三个挑战,该方法结合了单个卷积神经网络中胎盘位置(例如,前,后部)和语义胎盘分段的分类。通过分类任务,模型可以从更大,更多样化的数据集中学习,同时在有限的训练设置条件下提高了细分任务的准确性。通过这种方法,我们调查了多个评估者的注释的变异性,并表明我们的自动分割(前胎盘的骰子为0.86,后胎盘的骰子为0.83),与观察者内和观察者间的变异性相比,我们的自动段性能达到了人级的性能。最后,我们的方法可以使用由三个阶段组成的多视图US采集管道提供整个胎盘分割:多探针图像采集,图像融合和图像分段。这会导致对较大结构的高质量分割,例如我们在我们中的胎盘,其图像伪影降低,这超出了单个探针的视野。

Automatic segmentation of the placenta in fetal ultrasound (US) is challenging due to the (i) high diversity of placenta appearance, (ii) the restricted quality in US resulting in highly variable reference annotations, and (iii) the limited field-of-view of US prohibiting whole placenta assessment at late gestation. In this work, we address these three challenges with a multi-task learning approach that combines the classification of placental location (e.g., anterior, posterior) and semantic placenta segmentation in a single convolutional neural network. Through the classification task the model can learn from larger and more diverse datasets while improving the accuracy of the segmentation task in particular in limited training set conditions. With this approach we investigate the variability in annotations from multiple raters and show that our automatic segmentations (Dice of 0.86 for anterior and 0.83 for posterior placentas) achieve human-level performance as compared to intra- and inter-observer variability. Lastly, our approach can deliver whole placenta segmentation using a multi-view US acquisition pipeline consisting of three stages: multi-probe image acquisition, image fusion and image segmentation. This results in high quality segmentation of larger structures such as the placenta in US with reduced image artifacts which are beyond the field-of-view of single probes.

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