论文标题
基于心率变异性分析改善心律失常的心律失常预测
Improved Cardiac Arrhythmia Prediction Based on Heart Rate Variability Analysis
论文作者
论文摘要
在过去的100年中,在临床实践中发现了许多类型的心室和心脏心律不齐,这些心律不齐是导致心脏猝死的主要因素。心室心动过速,心室纤颤和阵发性心房颤动是最常见的和危险的心律不齐,因此早期发现对于防止任何进一步的并发症并减少死亡至关重要。诸如起搏器之类的可植入设备通常用于心脏突然死亡的高风险的患者。尽管在医疗技术方面取得了巨大进步,但在有效管理普通心律失常方面仍面临重大挑战。本论文提出了新的心律不齐检测和预测方法,以区分心律不齐与非生命威胁性心脏事件,以增加检测可能导致死亡率的事件的可能性,并减少不必要的治疗干预的发生率。这些方法基于对心率变异性(HRV)信息的详细分析。工作的结果表明了提出的方法的良好性能,并支持其在资源约束的心室和心律失常预测中部署的潜力,例如可植入的起搏器和除颤器。
Many types of ventricular and atrial cardiac arrhythmias have been discovered in clinical practice in the past 100 years, and these arrhythmias are a major contributor to sudden cardiac death. Ventricular tachycardia, ventricular fibrillation, and paroxysmal atrial fibrillation are the most commonly-occurring and dangerous arrhythmias, therefore early detection is crucial to prevent any further complications and reduce fatalities. Implantable devices such as pacemakers are commonly used in patients at high risk of sudden cardiac death. While great advances have been made in medical technology, there remain significant challenges in effective management of common arrhythmias. This thesis proposes novel arrhythmia detection and prediction methods to differentiate cardiac arrhythmias from non-life-threatening cardiac events, to increase the likelihood of detecting events that may lead to mortality, as well as reduce the incidence of unnecessary therapeutic intervention. The methods are based on detailed analysis of Heart Rate Variability (HRV) information. The results of the work show good performance of the proposed methods and support the potential for their deployment in resource-constrained devices for ventricular and atrial arrhythmia prediction, such as implantable pacemakers and defibrillators.