论文标题
基于AI的医学电子诊断,用于正常压力脑积水患者的快速和自动心室体积测量
AI-based Medical e-Diagnosis for Fast and Automatic Ventricular Volume Measurement in the Patients with Normal Pressure Hydrocephalus
论文作者
论文摘要
基于从正常压力脑积水(NPH)患者获得的CT和MRI图像,使用机器学习方法,我们旨在建立一种多模式和高性能自动心室分割方法,以实现对心室体积的有效自动测量。首先,我们提取143例NPH患者的脑CT和MRI图像。其次,我们手动标记心室体积(VV)和颅内体积(ICV)。然后,我们使用机器学习方法提取功能并建立自动心室分割模型。最后,我们验证模型的可靠性并实现了VV和ICV的自动测量。在CT图像中,VV的自动和手动分割结果的骰子相似系数(DSC),类内相关系数(ICC),Pearson相关性和平淡的Altman分析分别为0.95、0.99、0.99,0.99和4.2 $ \ pm PM $ 2.6。 ICV的结果分别为0.96、0.99、0.99和6.0 $ \ pm $ 3.8。整个过程需要3.4 $ \ pm $ 0.3秒。在MRI图像中,VV的自动和手动分割结果的DSC,ICC,Pearson相关性和Bland-Altman分析分别为0.94、0.99、0.99和2.0 $ \ pm $ 0.6。 ICV的结果分别为0.93、0.99、0.99和7.9 $ \ pm $ 3.8。整个过程花费了1.9 $ \ pm $ 0.1秒。我们已经建立了一种多模式和高性能自动心室分割方法,以实现NPH患者心室体积的有效,准确的自动测量。这可以帮助临床医生快速,准确地了解NPH患者心室的状况。
Based on CT and MRI images acquired from normal pressure hydrocephalus (NPH) patients, using machine learning methods, we aim to establish a multi-modal and high-performance automatic ventricle segmentation method to achieve efficient and accurate automatic measurement of the ventricular volume. First, we extract the brain CT and MRI images of 143 definite NPH patients. Second, we manually label the ventricular volume (VV) and intracranial volume (ICV). Then, we use machine learning method to extract features and establish automatic ventricle segmentation model. Finally, we verify the reliability of the model and achieved automatic measurement of VV and ICV. In CT images, the Dice similarity coefficient (DSC), Intraclass Correlation Coefficient (ICC), Pearson correlation, and Bland-Altman analysis of the automatic and manual segmentation result of the VV were 0.95, 0.99, 0.99, and 4.2$\pm$2.6 respectively. The results of ICV were 0.96, 0.99, 0.99, and 6.0$\pm$3.8 respectively. The whole process takes 3.4$\pm$0.3 seconds. In MRI images, the DSC, ICC, Pearson correlation, and Bland-Altman analysis of the automatic and manual segmentation result of the VV were 0.94, 0.99, 0.99, and 2.0$\pm$0.6 respectively. The results of ICV were 0.93, 0.99, 0.99, and 7.9$\pm$3.8 respectively. The whole process took 1.9$\pm$0.1 seconds. We have established a multi-modal and high-performance automatic ventricle segmentation method to achieve efficient and accurate automatic measurement of the ventricular volume of NPH patients. This can help clinicians quickly and accurately understand the situation of NPH patient's ventricles.