论文标题
对未采样4D流MRI的重建噪声的分析
An analysis of reconstruction noise from undersampled 4D flow MRI
论文作者
论文摘要
新型的磁共振(MR)成像方式可以量化血液动力学,但需要长时间的获得时间,从而排除了其在早期诊断心血管疾病的广泛使用。为了减少采集时间,通常使用来自未采样测量的重建方法,以利用旨在提高图像可压缩性的表示。 重建的解剖学和血液动力学图像可能会呈现视觉伪影。尽管其中一些伪像本质上是重建误差,因此是导致采样的结果,但其他人可能是由于测量噪声或采样频率的随机选择所致。否则说,重建的图像成为一个随机变量,其偏见及其协方差都会导致视觉伪像。后者导致空间相关性可能误解了视觉信息。尽管在文献中已经研究了前者的性质,但后者并没有得到太多关注。 在这项研究中,我们研究了由重建过程引起的随机扰动的理论特性,并对模拟和MR主动脉流进行了许多数值实验。我们的结果表明,当高斯底采样模式与基于$ \ ell_1 $ -norm最小化的恢复算法结合使用时,相关长度仍限制为2至3个像素。但是,对于其他不足采样模式,较高的不足采样因子(即8倍或16倍压缩)以及不同的重建方法,相关长度可能会显着增加。
Novel Magnetic Resonance (MR) imaging modalities can quantify hemodynamics but require long acquisition times, precluding its widespread use for early diagnosis of cardiovascular disease. To reduce the acquisition times, reconstruction methods from undersampled measurements are routinely used, that leverage representations designed to increase image compressibility. Reconstructed anatomical and hemodynamic images may present visual artifacts. Although some of these artifact are essentially reconstruction errors, and thus a consequence of undersampling, others may be due to measurement noise or the random choice of the sampled frequencies. Said otherwise, a reconstructed image becomes a random variable, and both its bias and its covariance can lead to visual artifacts; the latter leads to spatial correlations that may be misconstrued for visual information. Although the nature of the former has been studied in the literature, the latter has not received as much attention. In this study, we investigate the theoretical properties of the random perturbations arising from the reconstruction process, and perform a number of numerical experiments on simulated and MR aortic flow. Our results show that the correlation length remains limited to two to three pixels when a Gaussian undersampling pattern is combined with recovery algorithms based on $\ell_1$-norm minimization. However, the correlation length may increase significantly for other undersampling patterns, higher undersampling factors (i.e., 8x or 16x compression), and different reconstruction methods.