论文标题
阿根廷Covid-19传播的流行病模型:探索交替的隔离和大规模测试策略
An epidemic model for COVID-19 transmission in Argentina: Exploration of the alternating quarantine and massive testing strategies
论文作者
论文摘要
COVID-19大流行对全球政府不同级别的政府行政管理部门提出了挑战。当面对这种严重性的疾病时,对于当局来说,拥有预测工具以提前估算对卫生系统以及必要的人类,物质和经济资源的影响非常有用。在本文中,我们构建了一个扩展的受易感性感染的模型,该模型结合了Mar del Plata的社会结构,Mar del Plata是阿根廷的$ 4^\ cicc $,以及普埃里雷德将军的负责人。此外,我们根据疾病的严重性以及当地卫生资源的数据考虑了受感染者的详细分区,以使这些预测更接近当地现实。调整了Covid-19的相应流行参数,我们研究了一种交替的隔离策略,其中一部分人口可以随时无限制地循环,而其余的则分为两组,并连续进行正常活动和锁定期,每个持续时间为$τ$ $τ$。此外,我们对人群实施随机测试策略。我们发现$τ= 7 $是隔离策略的一个不错的选择,因为它与每周周期相匹配,因为它减少了感染人群。鉴于所需的机动性极低,我们预见到了9月30日的卫生系统,从9月30日开始的情况下,我们很难避免ICU饱和。在最坏的情况下,我们的模型估计将发生四千人死亡,其中30%可以通过适当的医疗救助避免。尽管如此,我们发现积极的测试将允许增加不限制的人的百分比,这是与其他关键患者打交道所需的设备相对较低。
The COVID-19 pandemic has challenged authorities at different levels of government administration around the globe. When faced with diseases of this severity, it is useful for the authorities to have prediction tools to estimate in advance the impact on the health system and the human, material, and economic resources that will be necessary. In this paper, we construct an extended Susceptible-Exposed-Infected-Recovered model that incorporates the social structure of Mar del Plata, the $4^\circ$ most inhabited city in Argentina and head of the Municipality of General Pueyrredón. Moreover, we consider detailed partitions of infected individuals according to the illness severity, as well as data of local health resources, to bring these predictions closer to the local reality. Tuning the corresponding epidemic parameters for COVID-19, we study an alternating quarantine strategy, in which a part of the population can circulate without restrictions at any time, while the rest is equally divided into two groups and goes on successive periods of normal activity and lockdown, each one with a duration of $τ$ days. Besides, we implement a random testing strategy over the population. We found that $τ= 7$ is a good choice for the quarantine strategy since it matches with the weekly cycle as it reduces the infected population. Focusing on the health system, projecting from the situation as of September 30, we foresee a difficulty to avoid saturation of ICU, given the extremely low levels of mobility that would be required. In the worst case, our model estimates that four thousand deaths would occur, of which 30\% could be avoided with proper medical attention. Nonetheless, we found that aggressive testing would allow an increase in the percentage of people that can circulate without restrictions, being the equipment required to deal with the additional critical patients relatively low.