论文标题
基于倒流反应堆概念的病毒性面膜，用于SARS-COV-2的热灭活
A Virucidal Face Mask Based on the Reverse-flow Reactor Concept for Thermal Inactivation of SARS-CoV-2
论文作者
论文摘要
虽然鼻子和嘴巴上的面部覆盖物通过过滤减少了病毒SARS-COV-2的扩散，但通过加热而能够病毒灭活的口罩可以提供一种互补的方法来限制病毒传播。在这项工作中，我们基于由人类呼吸的振荡流驱动的反向反应堆引入了一种新的病毒面膜概念。制定并解决了管理热和质量传输方程，以分析在吸入和呼气过程中评估病毒和二氧化碳传输的设计。鉴于人类呼吸的体积和频率所施加的限制，SARS-COV-2热灭活的动力学以及人类的安全和舒适性，加热的面具可能会使SARS-COV-2在流入和流出到医疗等级不育中。 We detail one particular design, with a volume of 300 mL at 90 $^\circ$C, that achieves a 3-log reduction in viral load with minimal viral impedance within the mask mesh, with partition coefficient around 2. This study is the first quantitative analysis of virucidal thermal inactivation within a protective face mask and addresses a pressing need for new approaches for personal protective equipment during a global pandemic.
While facial coverings over the nose and mouth reduce the spread of the virus SARS-CoV-2 by filtration, masks capable of viral inactivation by heating could provide a complementary method to limit viral transmission. In this work, we introduce a new virucidal face mask concept based on a reverse-flow reactor driven by the oscillatory flow of human breath. The governing heat and mass transport equation are formulated and solved to analyze designs that evaluate both viral and CO2 transport during inhalation and exhalation. Given limits imposed by the volume and frequency of human breath, the kinetics of SARS-CoV-2 thermal inactivation, and human safety and comfort, heated masks may inactivate SARS-CoV-2 in inflow and outflow to medical grade sterility. We detail one particular design, with a volume of 300 mL at 90 $^\circ$C, that achieves a 3-log reduction in viral load with minimal viral impedance within the mask mesh, with partition coefficient around 2. This study is the first quantitative analysis of virucidal thermal inactivation within a protective face mask and addresses a pressing need for new approaches for personal protective equipment during a global pandemic.
