论文标题
关于与非整倍性相关的转录组特征和一般应力状态
On the Transcriptomic Signature and General Stress State Associated with Aneuploidy
论文作者
论文摘要
具有多种核型的非整倍体细胞是否具有任何共同特性，这是一个引起人们强烈关注的主题。 Terhorst等人最近的一项研究。 （1）重新研究了常见的非整倍性基因表达（CAGE），提出了我们最近工作的结论（2）。在这篇简短的文章中，已将其作为给编辑的信件提交给PNA，我们解释了我们对Terhorst等人的主要担忧。以及为什么我们认为我们以前的结论是有效的。
Whether aneuploid cells with diverse karyotypes have any properties in common has a been a subject of intense interest. A recent study by Terhorst et al. (1) reinvestigated the common aneuploidy gene expression (CAGE), disputing the conclusion of our recent work (2). In this short article, which has been submitted to PNAS as a Letter to the Editor, we explain our major concerns about Terhorst et al. and why we believe that our previous conclusion stands valid.
