论文标题
单元可以移动多少方式：主动跌落的自我传播模式
How many ways a cell can move: the modes of self-propulsion of an active drop
论文作者
论文摘要
已经提出了许多物理模型，以解释细胞运动如何从内部活动中出现，主要集中于爬行运动是如何源于内部过程的。在这里，我们提供了基于一般物理原理的自我推广机制的分类，表明爬行并不是细胞在底物上移动的唯一途径。 We consider a thin drop of active matter on a planar substrate and fully characterize its autonomous motion for all three possible sources of driving: (i) the stresses induced in the bulk by active components, which allow in particular tractionless motion, (ii) the self-propulsion of active components at the substrate, which gives rise to crawling motion, and (iii) a net capillary force, possibly self-generated, and coupled to internal activity.我们确定对润滑方程的旅行波解，作为每种运动模式的无量纲活动参数的函数。数值模拟用于表征在广泛的活性幅度上的降落运动，并且与模拟的明确分析解决方案在弱活性状态下得出。
Numerous physical models have been proposed to explain how cell motility emerges from internal activity, mostly focused on how crawling motion arises from internal processes. Here we offer a classification of self-propulsion mechanisms based on general physical principles, showing that crawling is not the only way for cells to move on a substrate. We consider a thin drop of active matter on a planar substrate and fully characterize its autonomous motion for all three possible sources of driving: (i) the stresses induced in the bulk by active components, which allow in particular tractionless motion, (ii) the self-propulsion of active components at the substrate, which gives rise to crawling motion, and (iii) a net capillary force, possibly self-generated, and coupled to internal activity. We determine travelling-wave solutions to the lubrication equations as a function of a dimensionless activity parameter for each mode of motion. Numerical simulations are used to characterize the drop motion over a wide range of activity magnitudes, and explicit analytical solutions in excellent agreement with the simulations are derived in the weak-activity regime.
